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VirusREvolution​

About Us

Posted: October 13, 2023

Vision and Scientific Rationale A comprehensive understanding of viruses—including their diversity, pathogenic potential, and host tropism—requires advanced bioinformatic and photonic tools. Although Germany hosts internationally recognised expertise in virology, bioinformatics, and photonics, sustained and systematic integration of these disciplines has so far been limited, with notable exceptions such as HIV-1, Influenza A virus, and SARS-CoV-2. […]

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Team

  • Manja Marz (Spokesperson), Virus bioinformatics, RNA bioinformatics, HTS data analysis | FSU Jena, Institute for Computer Science
  • Sebastian Böcker (Coordination team), Bioinformatics, algorithmics, metabolomics | FSU Jena, Institute for Computer Science
  • Stefanie Deinhardt-Emmer (Coordination team), Pathogenesis of viral and bacterial interferences | FSU Jena, Institute of Medical Microbiology
  • Christian Eggeling (Coordination team), Super-resolution microscopy | FSU Jena, Institute for Applied Optics and Biophysics
  • Friedemann Weber (Coordination team), RNA viruses, innate immune response | JLU Giessen, Institute of Virology
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Research Programme

Research Goals

Posted: October 17, 2023

Overarching research goal of the CRC VirusREvolution The bold vision of the CRC VirusREvolution is to enable the rapid risk assessment of newly emerging viruses by integrating next-generation bioinformatics and photonic approaches. Our central goal is to establish the CRC platform capable of systematically characterising novel viruses, elucidate their tropism, and providing first estimations of […]

  • G1 Tools for the systematic characterisation of novel viruses.
  • G2 Tools for precise and comparative analysis of virus evolution.
  • G3 Tools for the generalisation and quantification of virus-host interactions.
  • G4 Tools for the early assessment and prediction of virus infection potential.
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Projects

To achieve our objective we establish three project areas to tackle various tasks:

Project Area A:
Tools for nucleotide sequences and regulation

Project Area B:
Tools for Virus Interaction and Structure

Project Area C:
Tools for morphology, entry and photonic signatures

Project Area Z:
Integrating activities and central tasks

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Long-term-Perspective

Long-term Perspective

Posted: October 17, 2023

Quite relentlessly, the COVID-19 crisis made transparent the lack of bioinformatic and photonic tools to understand even basic features of virus replication or, more strategically, approaches to fight outbreaks. The VirusREvolution initiative will provide virologists with the appropriate methods and tools to boost their knowledge of virus replication. The bioinformatics tools and photonic methods will […]

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Events